Eating fruit and vegetables, apart from the many well-known nutritional benefits it brings, would also have a clear anti-aging function.
Eating fruit has multiple health benefits. Just thinking about the great variety that both fruits and vegetables contain, many of them forgotten within the ultra-processed foods that make up the terrible Western Diet, is enough to realize the great nutritional treasure that these foods hide. In fact, many of these ultra-processed ones use advertising messages where they pride themselves on containing X or Y nutrients, trying to imitate fruits and vegetables.
One of the many substances that are often mentioned as beneficial when eating fruit or vegetables are usually " flavonoids ", which also accompany the nutritional statements of other foods, such as dark chocolate or even wine; although in the latter case we know that the harms (alcohol) outweigh the benefits.
Now, new research, recently published in the journal EBioMedicine, has concluded that a particular flavonoid found in various fruits and vegetables has a potential new effect: It can keep us younger.
The anti-aging effects of eating fruit
The fisetin, a flavonoid that can be found in many fruits and vegetables, would that natural flavonoid, whose senolítico effect would grant such potential. In other words, this flavonoid would be able to eliminate cells damaged in the body due to aging, thus being able to improve general health and extend useful life.
We must bear in mind that aging is something natural that cannot be eliminated in human life, but it takes nothing more than to go outside to realize that some individuals cope better than others: human aging does not understand age, but feeding. That is, although it is true that (logically), "the older, the more aging", it is possible to delay this natural process, either through good genetics, or through a good diet.
Every so often, human cells, from any part of the body, end up losing their ability to divide effectively and the immune system "cleanses" the trail when they die. But, as we age, the immune system also becomes less efficient and erratic in its task. Thus, damaged cells, or senescent cells, can accumulate and lead to chronic diseases related to age, and some of them can start even at an early age if a healthy lifestyle is not carried out. It is what is commonly called “aging badly”.
Although multiple investigations are currently being carried out with the aim of artificially eliminating the accumulation of these aging and harmful cells, the so-called senolytic drugs, such as those discussed in a study published in Nature in early 2018, the reality is that improving Its lifestyle in general would be crucial to avoid the accumulation of these cells.
Flavonoids, the anti-aging effect of eating fruit
All these senolytic drugs are based on the use of flavonoid compounds, and that is why it has been discovered that fisetin would be a potentially effective compound to prevent aging, both in mice and in humans. However, ideally, eating fruit and vegetables would be an alternative way to avoid such aging rather than resorting to medication.
In fact, fisetin was already known before, although its anti-aging potential had not been so directly exploited. As early as 2014, in a study published in Aging Cell, a fisetin-based compound was able to prevent the progression of Alzheimer's disease, although at that time only hypotheses could be made about fisetin and its potential, without being able to clearly link it to an anti-aging effect as such.
In this new research, thanks to a technology called mass cytometry, it has been possible to observe how the compound, a fisetin- based compound, would act within a senescent cell in a specific way, in mice. In addition, its effects on general health could also be verified, reducing biomarkers of age-related diseases and extending the average life expectancy of rodents.
Eating fruit: easier and more natural
At the moment almost all the research regarding flavonoids in general and fisetin in particular has been done in mice, and this particular work is still in its early stages. Still, since eating fruits and vegetables can provide fisetin and other flavonoids, these compounds being natural and easily accessible, the effects in humans are expected to be similar or even better.
Researchers hope to quickly reach clinical trials in humans, although the reality of the ordinary individual is easier and different, it is another level: the reality is that there is a lot of talk about developing this or that drug, but always emphasizing that They are based on natural compounds found in the supermarket. Therefore, the easy conclusion would be that eating fruit and vegetables, in quantity, as has always been recommended, and without the need to process them or extract their molecules in an artificial and isolated way, would be enough to improve our aging and even delay it.
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